The first cell therapy was performed about 80 years ago. In 1931, a Swiss physician named Dr Nyahans used bovine tissue transplantation to treat a disease in which he accidentally lost his parathyroid gland during thyroid surgery.
In 1959, the first unsuccessful bone marrow transplant was performed, though the first successful bone marrow transplant was performed in 1969. In 1970, corneal margin stem cells were used in corneal transplantation, and in 1979, stem cells were used to treat osteoarthritis. Based on the current data, in the last 15 years, 30 million cell therapies have been performed worldwide. So far, 19 cell therapy and gene therapy products have been approved by the US FDA. Skin diseases, including orthopedics, eye and prostate cancer, each one confirmed and other products are related to leukemia.